AHG testing includes detection of in vivo and in vitro sensitization. True or False?

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Multiple Choice

AHG testing includes detection of in vivo and in vitro sensitization. True or False?

Explanation:
AHG testing detects antibodies or complement bound to red blood cells both in the body and in laboratory tests. The direct antiglobulin test (DAT) identifies in vivo sensitization by detecting IgG or complement attached to a patient’s red cells. The indirect antiglobulin test (IAT) detects in vitro sensitization by allowing patient serum antibodies to react with reagent red cells in the test tube, then using AHG to reveal any antibody binding. Since AHG testing encompasses both DAT and IAT, the statement is true.

AHG testing detects antibodies or complement bound to red blood cells both in the body and in laboratory tests. The direct antiglobulin test (DAT) identifies in vivo sensitization by detecting IgG or complement attached to a patient’s red cells. The indirect antiglobulin test (IAT) detects in vitro sensitization by allowing patient serum antibodies to react with reagent red cells in the test tube, then using AHG to reveal any antibody binding. Since AHG testing encompasses both DAT and IAT, the statement is true.

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