Enzymes prevent detection of antibodies of which blood group system?

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Multiple Choice

Enzymes prevent detection of antibodies of which blood group system?

Explanation:
Enzymes used to treat red cells modify their surface by proteolysis, which can destroy some antigens. Duffy antigens are particularly susceptible to this, so antibodies against Duffy antigens (anti-Fya, anti-Fyb) may not react with enzyme-treated red cells. As a result, such antibodies can go undetected in routine screening when enzyme-treated cells are used. This is why the Duffy system is the one whose antibodies are commonly masked by enzyme treatment.

Enzymes used to treat red cells modify their surface by proteolysis, which can destroy some antigens. Duffy antigens are particularly susceptible to this, so antibodies against Duffy antigens (anti-Fya, anti-Fyb) may not react with enzyme-treated red cells. As a result, such antibodies can go undetected in routine screening when enzyme-treated cells are used. This is why the Duffy system is the one whose antibodies are commonly masked by enzyme treatment.

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