Red blood cells preserved with CPDA-1 expire after how many days?

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Multiple Choice

Red blood cells preserved with CPDA-1 expire after how many days?

Explanation:
Red blood cells stored with CPDA-1 have a shelf life of 35 days. CPDA-1 provides citrate anticoagulation plus phosphate, dextrose, and adenine to support metabolism and ATP production, which helps preserve RBC integrity longer than older anticoagulants. Keeping units at 1–6°C, the quality remains acceptable for up to 35 days; after that, changes in energy stores and membrane stability increase the risk of hemolysis and reduced oxygen delivery. If additive solutions are used with RBCs, shelf life can be extended to 42 days, but with CPDA-1 alone the limit is 35 days. The 21-day option corresponds to CPD, and 1 year is not feasible for stored RBCs.

Red blood cells stored with CPDA-1 have a shelf life of 35 days. CPDA-1 provides citrate anticoagulation plus phosphate, dextrose, and adenine to support metabolism and ATP production, which helps preserve RBC integrity longer than older anticoagulants. Keeping units at 1–6°C, the quality remains acceptable for up to 35 days; after that, changes in energy stores and membrane stability increase the risk of hemolysis and reduced oxygen delivery. If additive solutions are used with RBCs, shelf life can be extended to 42 days, but with CPDA-1 alone the limit is 35 days. The 21-day option corresponds to CPD, and 1 year is not feasible for stored RBCs.

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