The immediate spin crossmatch is used to detect which of the following?

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Multiple Choice

The immediate spin crossmatch is used to detect which of the following?

Explanation:
Immediate spin crossmatch checks for ABO incompatibility by testing whether the recipient’s naturally occurring anti-ABO antibodies will agglutinate donor red cells at room temperature. ABO antibodies are predominantly IgM and react quickly, so a mismatch in ABO antigens between donor cells and recipient plasma produces visible agglutination during the spin. Incompatibilities involving Rh, Kell, or Duffy are usually due to IgG antibodies that react best in the antiglobulin phase, not at the immediate spin, so they aren’t reliably detected in this test. That’s why the immediate spin crossmatch is focused on detecting ABO incompatibility.

Immediate spin crossmatch checks for ABO incompatibility by testing whether the recipient’s naturally occurring anti-ABO antibodies will agglutinate donor red cells at room temperature. ABO antibodies are predominantly IgM and react quickly, so a mismatch in ABO antigens between donor cells and recipient plasma produces visible agglutination during the spin. Incompatibilities involving Rh, Kell, or Duffy are usually due to IgG antibodies that react best in the antiglobulin phase, not at the immediate spin, so they aren’t reliably detected in this test. That’s why the immediate spin crossmatch is focused on detecting ABO incompatibility.

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