Warm autoimmune hemolytic anemia antibodies are typically of which immunoglobulin class?

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Multiple Choice

Warm autoimmune hemolytic anemia antibodies are typically of which immunoglobulin class?

Explanation:
Warm autoimmune hemolytic anemia is driven by autoantibodies that react with red cells at body temperature. The immunoglobulin class most commonly involved is IgG, which binds to red cell antigens and is cleared mainly by Fc receptors in the spleen, producing extravascular hemolysis. IgM is typically associated with cold agglutinin disease, where complement activation can cause intravascular hemolysis. IgA and IgE are not typical players in AIHA. So the class most linked to warm AIHA is IgG.

Warm autoimmune hemolytic anemia is driven by autoantibodies that react with red cells at body temperature. The immunoglobulin class most commonly involved is IgG, which binds to red cell antigens and is cleared mainly by Fc receptors in the spleen, producing extravascular hemolysis. IgM is typically associated with cold agglutinin disease, where complement activation can cause intravascular hemolysis. IgA and IgE are not typical players in AIHA. So the class most linked to warm AIHA is IgG.

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