Which blood group lacks A and B antigens on the surface of its red blood cells?

Prepare for the MT AAB Immunohematology Test with our engaging online quiz. Study with multiple-choice questions and detailed explanations. Boost your understanding and be exam-ready!

Multiple Choice

Which blood group lacks A and B antigens on the surface of its red blood cells?

Explanation:
Red blood cell A and B antigens are produced by specific enzymes that modify the H antigen on the cell surface. If neither enzyme is present, the cell displays only the H antigen and lacks A and B antigens. This phenotype is type O. People with type O have anti-A and anti-B antibodies in their plasma, which is why their red cells can be given to anyone (universal donor) for transfusions, since the donor cells themselves do not carry A or B antigens.

Red blood cell A and B antigens are produced by specific enzymes that modify the H antigen on the cell surface. If neither enzyme is present, the cell displays only the H antigen and lacks A and B antigens. This phenotype is type O. People with type O have anti-A and anti-B antibodies in their plasma, which is why their red cells can be given to anyone (universal donor) for transfusions, since the donor cells themselves do not carry A or B antigens.

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